N,N'-Diisopropylcarbodiimide CAS 693-13-0

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N,N'-Diisopropylcarbodiimide (CAS 693-13-0), referred to as DIC, has strong dehydration and coupling properties and is used in organic synthesis and biochemistry.

1. Coupling agents in organic synthesis

N,N'-Diisopropylcarbodiimide is used as a coupling agent in organic chemistry to promote the formation of peptide bonds or ester bonds. It is particularly efficient in peptide synthesis and is often used in solid phase peptide synthesis (SPPS).

2. Application of biochemistry and medicinal chemistry

In biochemistry and drug synthesis, DIC helps improve the stability and bioavailability of drug molecules and is used in the synthesis of peptides and nucleic acids as well as the preparation of antibodies and vaccines.

3. Catalysis and dehydration reaction

N,N'-Diisopropylcarbodiimide acts as a dehydrating agent in catalytic reactions, effectively removing water from the reaction and promoting the reaction, especially in the synthesis of amines and amides.

4. Materials Science and Polymer Synthesis

In materials science, DIC is used in polymer synthesis, especially in the preparation of functional materials such as polyurethane, where it plays a role in coupling and cross-linking.

5. Andre anvendelser

N,N'-Diisopropylcarbodiimide is also used in chemical laboratories to participate in the synthesis of various chemical substances such as anhydrides, aldehydes, ketones, etc.

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